Contents
Vol 2, Issue 49
Contents
Commentary
- A Multi-Level Systems Perspective for the Science of Team Science
Understanding how teams function is vital because they are increasingly dominating the production of high-impact science.
Perspective
- GIP: No Longer the Neglected Incretin Twin?
A pair of complementary studies suggest that scientists consider the incretin hormone gastric inhibitory polypeptide as a new therapeutic target for Type 2 diabetes.
Research Articles
- Personalized Epigenomic Signatures That Are Stable Over Time and Covary with Body Mass Index
A genome-scale, gene-specific analysis of DNA methylation in the same individuals over a decade apart identifies a personalized epigenomic signature that may correlate with a common genetic trait.
- Disruption at the PTCHD1 Locus on Xp22.11 in Autism Spectrum Disorder and Intellectual Disability
Mutations of the X-linked gene PTCHD1 are associated with autism spectrum disorders and intellectual disability.
Editors' Choice
- A New “Fix” for Cancer
Overexpression of an oncogenic microRNA leads to pre–B cell lymphoma.
- Next-Generation Sequencing: A Better Way
The cost of next-generation sequencing can be lowered, without loss of power, by pooling samples from more subjects and sequencing at a lower depth.
- Molecular Snapshot
A new microfluidic device allows for easy isolation of neutrophils for genomic and proteomic analyses.