Platelet CD154 Potentiates Interferon-α Secretion by Plasmacytoid Dendritic Cells in Systemic Lupus Erythematosus

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  Platelet CD154 Potentiates Interferon-α Secretion by Plasmacytoid Dendritic Cells in Systemic Lupus Erythematosus

  By Pierre Duffau, Julien Seneschal, Carole Nicco, Christophe Richez, Estibaliz Lazaro, Isabelle Douchet, Cécile Bordes, Jean-François Viallard, Claire Goulvestre, Jean-Luc Pellegrin, Bernard Weil, Jean-François Moreau, Frédéric Batteux, Patrick Blanco

  Science Translational Medicine01 Sep 2010 : 47ra63

  In the autoimmune disease lupus, platelets activated by self-antigens contribute to pathology by triggering the secretion of interferon from immune cells.

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  Platelet CD154 Potentiates Interferon-α Secretion by Plasmacytoid Dendritic Cells in Systemic Lupus Erythematosus

  By Pierre Duffau, Julien Seneschal, Carole Nicco, Christophe Richez, Estibaliz Lazaro, Isabelle Douchet, Cécile Bordes, Jean-François Viallard, Claire Goulvestre, Jean-Luc Pellegrin, Bernard Weil, Jean-François Moreau, Frédéric Batteux, Patrick Blanco

  Science Translational Medicine01 Sep 2010 : 47ra63

  In the autoimmune disease lupus, platelets activated by self-antigens contribute to pathology by triggering the secretion of interferon from immune cells.

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