25 August 2010
Vol 2, Issue 46

About The Cover

Cover image expansion

ONLINE COVER Fiat Lux. A collage of biosynthetic substitutes of the human cornea. In work presented in this week's issue of Science Translational Medicine, Fagerholm et al. have engineered an optically clear, collagen-based corneal implant that mimics the natural human extracellular matrix to facilitate formation of a morphologically normal epithelium, to aid in nerve regeneration, and improve vision. The matrix uses a special water-based cross-linking reagent such that no toxic by-products enter the tissue. These implants provide powerful alternatives to the dwindling number of human cornea donors. [CREDIT: FAGERHOLM ET AL.]