18 August 2010
Vol 2, Issue 45

About The Cover

Cover image expansion

ONLINE COVER A Trick for Tighter Teeth. A titanium plug (black) implanted into bone (yellow and orange) is more tightly embraced by surrounding tissue coated with molecules that mimic the extracellular matrix. Petrie and colleagues attach a key portion of the extracellular matrix molecule fibronectin to the end of flexible linkers and then assemble these into clusters. These clusters mimic the natural molecular neighbors of bone cells and stimulate firm mechanical integration of the implant, a benefit for dental or orthopedic applications. [CREDIT: T. PETRIE]