Research ArticleCancer Drug Development

Pathway-Based Identification of Biomarkers for Targeted Therapeutics: Personalized Oncology with PI3K Pathway Inhibitors

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Science Translational Medicine  04 Aug 2010:
Vol. 2, Issue 43, pp. 43ra55
DOI: 10.1126/scitranslmed.3001065

Article Information

vol. 2 no. 43 43ra55

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication March 12, 2010
  • Accepted for publication July 16, 2010

Author Information

  1. Jannik N. Andersen1,*,
  2. Sriram Sathyanarayanan1,*,
  3. Alessandra Di Bacco1,
  4. An Chi1,
  5. Theresa Zhang1,
  6. Albert H. Chen1,
  7. Brian Dolinski1,
  8. Manfred Kraus1,
  9. Brian Roberts1,
  10. William Arthur2,
  11. Rich A. Klinghoffer1,,
  12. Diana Gargano1,,
  13. Lixia Li1,
  14. Igor Feldman1,
  15. Bethany Lynch1,
  16. John Rush3,
  17. Ronald C. Hendrickson4,§,
  18. Peter Blume-Jensen1,§|| and
  19. Cloud P. Paweletz1
  1. 1Merck Sharp & Dohme, Boston, MA 02115, USA.
  2. 2Merck Sharp & Dohme, North Wales, PA 19454, USA.
  3. 3Cell Signaling Technology, Danvers, MA 01923, USA.
  4. 4Merck Sharp & Dohme, Rahway, NJ 07065, USA.
  1. §To whom correspondence should be addressed. E-mail: ronald_hendrickson{at}merck.com (R.C.H.); pblume-jensen{at}dsi.com (P.B.-J.)

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