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Research ArticleCeliac Disease
Comprehensive, Quantitative Mapping of T Cell Epitopes in Gluten in Celiac Disease
- Jason A. Tye-Din1,2,3,*,
- Jessica A. Stewart1,*,
- James A. Dromey1,*,
- Tim Beissbarth1,*†,
- David A. van Heel4,
- Arthur Tatham5,
- Kate Henderson6,
- Stuart I. Mannering1,‡,
- Carmen Gianfrani7,
- Derek P. Jewell8,
- Adrian V. S. Hill9,
- James McCluskey10,
- Jamie Rossjohn6 and
- Robert P. Anderson1,3,§
- 1Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3052, Australia.
- 2Department of Medical Biology, University of Melbourne, Parkville, Victoria 3010, Australia.
- 3Department of Gastroenterology, Royal Melbourne Hospital, Grattan Street, Parkville, Victoria 3050, Australia.
- 4Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, UK.
- 5Cardiff School of Health Sciences, University of Wales Institute, Cardiff CF5 2YB, UK.
- 6Protein Crystallography Unit, Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria 3800, Australia.
- 7Institute of Food Science, National Research Council, Via Roma 52, 83100 Avellino, Italy.
- 8Nuffield Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.
- 9Jenner Institute, University of Oxford, Oxford OX3 9DU, UK.
- 10Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria 3010, Australia.
- §To whom correspondence should be addressed. E-mail: banderson{at}wehi.edu.au
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Science Translational Medicine 21 Jul 2010:
Vol. 2, Issue 41, pp. 41ra51
DOI: 10.1126/scitranslmed.3001012
Vol. 2, Issue 41, pp. 41ra51
DOI: 10.1126/scitranslmed.3001012
Jason A. Tye-Din
Jessica A. Stewart
James A. Dromey
Tim Beissbarth
David A. van Heel
Arthur Tatham
Kate Henderson
Stuart I. Mannering
Carmen Gianfrani
Derek P. Jewell
Adrian V. S. Hill
James McCluskey
Jamie Rossjohn
Robert P. Anderson
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