Research ArticleBreast Cancer Genetics

Genomic Architecture Characterizes Tumor Progression Paths and Fate in Breast Cancer Patients

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Science Translational Medicine  30 Jun 2010:
Vol. 2, Issue 38, pp. 38ra47
DOI: 10.1126/scitranslmed.3000611

Article Information

vol. 2 no. 38 38ra47

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication November 10, 2009
  • Accepted for publication June 4, 2010
  • .

Author Information

  1. Hege G. Russnes1,2,3,*,
  2. Hans Kristian Moen Vollan1,3,4,*,
  3. Ole Christian Lingjærde5,
  4. Alexander Krasnitz6,
  5. Pär Lundin7,
  6. Bjørn Naume8,
  7. Therese Sørlie1,
  8. Elin Borgen2,
  9. Inga H. Rye2,
  10. Anita Langerød1,
  11. Suet-Feung Chin9,
  12. Andrew E. Teschendorff9,10,
  13. Philip J. Stephens11,
  14. Susanne Månér7,
  15. Ellen Schlichting4,
  16. Lars O. Baumbusch1,2,5,
  17. Rolf Kåresen4,
  18. Michael P. Stratton11,12,
  19. Michael Wigler6,
  20. Carlos Caldas9,13,
  21. Anders Zetterberg7,
  22. James Hicks6, and
  23. Anne-Lise Børresen-Dale1,3,
  1. 1Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway.
  2. 2Division of Pathology, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway.
  3. 3Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0318 Oslo, Norway.
  4. 4Department of Breast and Endocrine Surgery, Division of Surgery and Cancer, Oslo University Hospital, 0450 Oslo, Norway.
  5. 5Biomedical Research Group, Department of Informatics, University of Oslo, P.O. Box 1080 Blindern, 0316 Oslo, Norway.
  6. 6Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
  7. 7Department of Oncology-Pathology, Karolinska Institutet, Cancer Center Karolinska, SE-171 76 Stockholm, Sweden.
  8. 8Department of Oncology, Division of Surgery and Cancer, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway.
  9. 9Breast Cancer Functional Genomics, Cancer Research UK Cambridge Research Institute and Department of Oncology, University of Cambridge, Li Ka-Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.
  10. 10UCL Cancer Institute, University College London, London WC1E 6BT, UK.
  11. 11Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
  12. 12Institute of Cancer Research, Sutton, Surrey SM2 5NG, UK.
  13. 13Cambridge Breast Unit, Addenbrookes Hospital and Cambridge National Institute for Health Research Biomedical Research Centre, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, UK.
  1. To whom correspondence should be addressed. E-mail: a.l.borresen-dale{at}medisin.uio.no

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