CommentaryHealth Reform

Patient-Centered Outcomes Research Institute: The Intersection of Science and Health Care

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Science Translational Medicine  23 Jun 2010:
Vol. 2, Issue 37, pp. 37cm18
DOI: 10.1126/scitranslmed.3001235


The Patient Protection and Affordable Care Act created the Patient-Centered Outcomes Research Institute (PCORI), a nonprofit corporation that is neither an agency nor an establishment of the U.S. government. PCORI’s mission is to support the production of well-validated scientific evidence to assist the nation in making informed decisions about a broad range of health care–related issues. In this Commentary, the directors of the Agency for Healthcare Research and Quality and the National Institutes of Health discuss PCORI’s opportunities to contribute to a robust portfolio of scientific inquiry that builds on their agencies’ investment in comparative effectiveness research.


  • Citation: C. Clancy, F. S. Collins, Patient-Centered Outcomes Research Institute: The intersection of science and health care. Sci. Transl. Med. 2, 37cm18 (2010).

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