Cystamine Suppresses Polyalanine Toxicity in a Mouse Model of Oculopharyngeal Muscular Dystrophy | Science Translational Medicine

Skip to main content

ScienceMag.org

Article Information

vol. 2 no. 34 34ra40

DOI:

https://doi.org/10.1126/scitranslmed.3000723

PubMed:

Published By:

American Association for the Advancement of Science

Print ISSN:

Online ISSN:

History:

Received for publication December 11, 2009
Accepted for publication May 10, 2010
.

Copyright & Usage:

Copyright © 2010, American Association for the Advancement of Science

Author Information

Janet E. Davies*,
Claudia Rose*,
Sovan Sarkar and
David C. Rubinsztein†

Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Addenbrooke’s Hospital, Hills Road, Cambridge CB2 0XY, UK.

†To whom correspondence should be addressed. E-mail: dcr1000{at}hermes.cam.ac.uk

Altmetric

Article usage

Article usage: May 2010 to August 2019

	Abstract	Full	Pdf
May 2010	9	2	0
Jun 2010	2529	86	148
Jul 2010	211	10	23
Aug 2010	133	4	11
Sep 2010	128	6	11
Oct 2010	173	10	11
Nov 2010	107	8	11
Dec 2010	80	2	10
Jan 2011	72	2	3
Feb 2011	83	1	7
Mar 2011	66	4	5
Apr 2011	66	1	1
May 2011	72	2	7
Jun 2011	61	4	5
Jul 2011	52	7	4
Aug 2011	45	1	4
Sep 2011	37	12	8
Oct 2011	49	3	4
Nov 2011	60	5	6
Dec 2011	53	1	1
Jan 2012	61	3	3
Feb 2012	58	1	2
Mar 2012	59	1	7
Apr 2012	37	2	4
May 2012	45	2	4
Jun 2012	32	1	2
Jul 2012	39	1	4
Aug 2012	43	4	4
Sep 2012	33	2	6
Oct 2012	27	4	4
Nov 2012	35	1	3
Dec 2012	23	0	0
Jan 2013	38	1	4
Feb 2013	13	2	1
Mar 2013	31	3	2
Apr 2013	40	2	2
May 2013	51	1	1
Jun 2013	58	3	4
Jul 2013	33	5	7
Aug 2013	27	1	4
Sep 2013	31	5	5
Oct 2013	29	4	5
Nov 2013	39	1	3
Dec 2013	29	3	2
Jan 2014	44	5	5
Feb 2014	30	4	4
Mar 2014	26	2	2
Apr 2014	39	3	4
May 2014	42	3	3
Jun 2014	17	7	3
Jul 2014	18	4	1
Aug 2014	13	0	3
Sep 2014	18	5	5
Oct 2014	14	6	2
Nov 2014	26	3	4
Dec 2014	32	1	2
Jan 2015	55	2	4
Feb 2015	12	1	1
Mar 2015	14	4	4
Apr 2015	30	1	1
May 2015	31	2	1
Jun 2015	22	2	1
Jul 2015	20	0	0
Aug 2015	22	0	3
Sep 2015	9	1	1
Oct 2015	1	0	0
Nov 2015	3	1	0
Dec 2015	9	0	1
Jan 2016	33	1	0
Feb 2016	30	0	1
Mar 2016	50	3	5
Apr 2016	25	0	1
May 2016	27	1	5
Jun 2016	82	5	1
Jul 2016	23	2	2
Aug 2016	24	4	4
Sep 2016	81	0	0
Oct 2016	23	0	1
Nov 2016	40	2	0
Dec 2016	31	0	1
Jan 2017	14	4	1
Feb 2017	21	4	2
Mar 2017	82	1	7
Apr 2017	52	0	1
May 2017	60	4	2
Jun 2017	22	0	1
Jul 2017	25	1	2
Aug 2017	44	2	0
Sep 2017	39	3	2
Oct 2017	29	4	1
Nov 2017	26	6	2
Dec 2017	36	2	0
Jan 2018	59	3	4
Feb 2018	52	6	4
Mar 2018	32	9	3
Apr 2018	43	4	2
May 2018	62	14	8
Jun 2018	45	2	0
Jul 2018	49	1	0
Aug 2018	20	2	1
Sep 2018	32	4	2
Oct 2018	33	1	2
Nov 2018	31	4	0
Dec 2018	22	4	1
Jan 2019	25	5	2
Feb 2019	27	3	2
Mar 2019	21	5	3
Apr 2019	31	7	2
May 2019	17	5	3
Jun 2019	16	5	0
Jul 2019	27	0	2
Aug 2019	1	2	0

Science Translational Medicine: 2 (34)

Science Translational Medicine

Vol 2, Issue 34
02 June 2010

Table of Contents

Article Tools

Email

Thank you for your interest in spreading the word about Science Translational Medicine.
NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Your Email

Your Name

Send To
Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Cystamine Suppresses Polyalanine Toxicity in a Mouse Model of Oculopharyngeal Muscular Dystrophy

Message Subject (Your Name) has forwarded a page to you from Science Translational Medicine

Message Body (Your Name) thought you would like to see this page from the Science Translational Medicine web site.

Your Personal Message
Download Powerpoint
Print
Save to my folders

Log In with your AAAS Login
Alerts

Please log in to add an alert for this article.

Log In with your AAAS Login

Sign In to Email Alerts with your Email Address
Email
Citation tools
Cystamine Suppresses Polyalanine Toxicity in a Mouse Model of Oculopharyngeal Muscular Dystrophy

By Janet E. Davies, Claudia Rose, Sovan Sarkar, David C. Rubinsztein

Science Translational Medicine02 Jun 2010 : 34ra40

Mice with oculopharyngeal muscular dystrophy, caused by aggregation of a nuclear protein, show improvement when treated with cystamine, suggesting a possible therapeutic approach for patients.

Citation Manager Formats

BibTeX

Bookends

EasyBib

EndNote (tagged)

EndNote 8 (xml)

Medlars

Mendeley

Papers

RefWorks Tagged

Ref Manager

RIS

Zotero
Share

Cystamine Suppresses Polyalanine Toxicity in a Mouse Model of Oculopharyngeal Muscular Dystrophy

By Janet E. Davies, Claudia Rose, Sovan Sarkar, David C. Rubinsztein

Science Translational Medicine02 Jun 2010 : 34ra40

Mice with oculopharyngeal muscular dystrophy, caused by aggregation of a nuclear protein, show improvement when treated with cystamine, suggesting a possible therapeutic approach for patients.

Share This Article:

Citing Articles in: