Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Addenbrooke’s Hospital, Hills Road, Cambridge CB2 0XY, UK.
†To whom correspondence should be addressed. E-mail: dcr1000{at}hermes.cam.ac.uk
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Science Translational Medicine 02 Jun 2010: Vol. 2, Issue 34, pp. 34ra40 DOI: 10.1126/scitranslmed.3000723
Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Addenbrooke’s Hospital, Hills Road, Cambridge CB2 0XY, UK.
†To whom correspondence should be addressed. E-mail: dcr1000{at}hermes.cam.ac.uk
Cystamine Suppresses Polyalanine Toxicity in a Mouse Model of Oculopharyngeal Muscular Dystrophy
By Janet E. Davies, Claudia Rose, Sovan Sarkar, David C. Rubinsztein
Science Translational Medicine : 34ra40
Mice with oculopharyngeal muscular dystrophy, caused by aggregation of a nuclear protein, show improvement when treated with cystamine, suggesting a possible therapeutic approach for patients.
Cystamine Suppresses Polyalanine Toxicity in a Mouse Model of Oculopharyngeal Muscular Dystrophy
By Janet E. Davies, Claudia Rose, Sovan Sarkar, David C. Rubinsztein
Science Translational Medicine : 34ra40
Mice with oculopharyngeal muscular dystrophy, caused by aggregation of a nuclear protein, show improvement when treated with cystamine, suggesting a possible therapeutic approach for patients.