Contents
Vol 2, Issue 33
Contents
Perspectives
- Achalasia and Viral Infection: New Insights from Veterinary Medicine
A viral disease in parrots mimics features of achalasia, a human disorder of esophageal motility, raising the possibility of an infectious cause for this human disease.
- Rong’s Numbers: Accelerating Progress in HCV Therapeutic Research
Therapeutic research on hepatitis C virus should be expedited with hypothesis-driven clinical trials that are supported by state-of-the-art translational research tools and mathematical modeling, as was done 15 years ago for AIDS.
Research Articles
- Metabolic Signatures of Exercise in Human Plasma
Measurement by mass spectrometry of 200 blood metabolites reveals that individuals who are more fit respond more effectively to exercise, as shown by larger exercise-induced increase in glycerol.
- Proteins Required for Centrosome Clustering in Cancer Cells
Identified in an RNA interference screen, proteins that prevent spindle multipolarity in human cancer cells may prove to be promising drug targets.
Editors' Choice
- New Hope for Premature Newborns
A recently characterized enzyme is required for the production of a key component of lung surfactant and facilitates the transition to air breathing.
- Could Interleukin-33 Be the Stopgap Against Sepsis?
Interleukin-33 improves survival in mice with sepsis and is low in patients who did not survive sepsis.
- Crime Is Its Own Reward
Excessive dopamine signaling in the brain’s reward system may underlie antisocial behavior.
- Differentiation Block in Glioma
The glioma genome project leads to the discovery of an oncogene that may promote tumor formation by blocking differentiation of neural stem cells.
