05 May 2010
Vol 2, Issue 30
  • Contents

    • Commentaries

    • Research Article

    • Editors' Choice

      • Smokers—Keap Quitting!

        Sustained activation of a transcription factor that promotes an antioxidant response reduces cigarette smoke–induced oxidative stress in lungs.

      • Sudden Death in Epilepsy: A Shot to the Heart?

        Altered neural signaling during seizures can lead to fatal cardiac arrhythmias, possibly accounting for sudden unexplained deaths in patients with epilepsy.

      • Your Genome Is Ready

        Whole-genome sequencing will soon become easily available, but many challenges lie ahead.

    • Podcast

      • Science Translational Medicine Podcast: 5 May 2010

        A conversation with Science Translational Medicine's Senior Scientific Advisor about the unique challenges and benefits of combining engineering and biology in translational medicine.

About The Cover

Cover image expansion

ONLINE COVER Clinical Trials and the Internet: Using Its Power for Good. The Internet has the potential to transform authority and trust relations of all kinds. Nothing like it in scale has occurred since the invention of the printing press. In this week's Commentary, Martensen opines on opportunities the Internet provides for researchers and their institutional review boards to secure their status as trusted sources. Intelligent use of the Internet can aid in the quest to improve the clinical-trial design, approval, and participant-recruitment processes. [CREDIT: C. BICKEL/SCIENCE TRANSLATIONAL MEDICINE]