Contents
Vol 2, Issue 30
Contents
Commentaries
- Institutional Review Boards, Professionalism, and the Internet
Researchers and review boards must work to improve clinical protocol design and approval procedures and maintain the integrity of the study participant recruitment process in clinical trials.
- Driving Drug Discovery: The Fundamental Role of Academic Labs
Researchers at academic labs make almost all of the basic science discoveries that underlie the creation of innovative new medicines.
Research Article
- Rapid Emergence of Protease Inhibitor Resistance in Hepatitis C Virus
Computational modeling suggests that the rapid emergence of resistance to drugs against hepatitis C virus is a result of preexisting resistant virus and potent suppression of wild-type virus.
Editors' Choice
- Smokers—Keap Quitting!
Sustained activation of a transcription factor that promotes an antioxidant response reduces cigarette smoke–induced oxidative stress in lungs.
- Resolvins Balm Your Pain in Flesh and Brain
The lipid mediators resolvins alleviate pain through both central and peripheral pathways.
- Sudden Death in Epilepsy: A Shot to the Heart?
Altered neural signaling during seizures can lead to fatal cardiac arrhythmias, possibly accounting for sudden unexplained deaths in patients with epilepsy.
- Your Genome Is Ready
Whole-genome sequencing will soon become easily available, but many challenges lie ahead.
Podcast
- Science Translational Medicine Podcast: 5 May 2010
A conversation with Science Translational Medicine's Senior Scientific Advisor about the unique challenges and benefits of combining engineering and biology in translational medicine.
