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Research ArticleCystic Fibrosis
Cystic Fibrosis Pigs Develop Lung Disease and Exhibit Defective Bacterial Eradication at Birth
- David A. Stoltz1,
- David K. Meyerholz2,
- Alejandro A. Pezzulo1,
- Shyam Ramachandran3,
- Mark P. Rogan1,
- Greg J. Davis1,
- Robert A. Hanfland4,
- Chris Wohlford-Lenane3,
- Cassie L. Dohrn2,
- Jennifer A. Bartlett3,
- George A. Nelson IV1,
- Eugene H. Chang5,
- Peter J. Taft1,
- Paula S. Ludwig1,
- Mira Estin1,
- Emma E. Hornick1,
- Janice L. Launspach1,
- Melissa Samuel6,
- Tatiana Rokhlina1,
- Philip H. Karp1,7,
- Lynda S. Ostedgaard1,
- Aliye Uc3,
- Timothy D. Starner3,
- Alexander R. Horswill8,
- Kim A. Brogden9,
- Randall S. Prather6,
- Sandra S. Richter2,
- Joel Shilyansky4,
- Paul B. McCray Jr.3,
- Joseph Zabner1 and
- Michael J. Welsh1,7,10,*
- 1Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
- 2Department of Pathology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
- 3Department of Pediatrics, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
- 4Department of Surgery, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
- 5Department of Otolaryngology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
- 6Division of Animal Sciences, University of Missouri, Columbia, MO 65211, USA.
- 7Howard Hughes Medical Institute, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
- 8Department of Microbiology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
- 9Department of Periodontics and Dows Institute for Dental Research, College of Dentistry, University of Iowa, Iowa City, IA 52242, USA.
- 10Department of Molecular Physiology and Biophysics, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
- *To whom correspondence should be addressed. E-mail: michael-welsh{at}uiowa.edu
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Science Translational Medicine 28 Apr 2010:
Vol. 2, Issue 29, pp. 29ra31
DOI: 10.1126/scitranslmed.3000928
Vol. 2, Issue 29, pp. 29ra31
DOI: 10.1126/scitranslmed.3000928
David A. Stoltz
David K. Meyerholz
Alejandro A. Pezzulo
Shyam Ramachandran
Mark P. Rogan
Greg J. Davis
Robert A. Hanfland
Chris Wohlford-Lenane
Cassie L. Dohrn
Jennifer A. Bartlett
George A. Nelson IV
Eugene H. Chang
Peter J. Taft
Paula S. Ludwig
Mira Estin
Emma E. Hornick
Janice L. Launspach
Melissa Samuel
Tatiana Rokhlina
Philip H. Karp
Lynda S. Ostedgaard
Aliye Uc
Timothy D. Starner
Alexander R. Horswill
Kim A. Brogden
Randall S. Prather
Sandra S. Richter
Joel Shilyansky
Paul B. McCray Jr.
Joseph Zabner
Michael J. Welsh
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