Contents
Vol 2, Issue 29
Contents
Commentary
- Six Questions About Translational Due Diligence
To maintain public support, the translational research enterprise must do more than provide results.
Perspective
- The Development of Lung Disease in Cystic Fibrosis Pigs
A new study finds that cystic fibrosis pigs develop key features of the often-lethal lung disease seen in cystic fibrosis patients.
Research Articles
- Wnt Proteins Promote Bone Regeneration
A liposome-encased ligand for the Wnt signaling pathway can accelerate bone regeneration after injury.
- Cystic Fibrosis Pigs Develop Lung Disease and Exhibit Defective Bacterial Eradication at Birth
The lungs of just-born piglets with cystic fibrosis fail to efficiently eliminate bacteria, suggesting that lung problems in cystic fibrosis patients may be secondary to impaired antibacterial defense mechanisms.
Editors' Choice
- Keep Monkeying Around
Induced pluripotent stem cells from nonhuman primates can be used as a model of autologous cell therapy.
- A BRCA3 Gene?
Protein-altering variants in the newly designated oncogene, RAD51C, confers substantial risk for developing gynecologic malignancies in a study of 1100 pedigrees with breast and ovarian cancer.
- What to Ingest When You’re Expecting
High doses of antioxidant vitamins may not prevent complications from pregnancy-associated high blood pressure.
- Inspiration on Perspiration: Putting Sweat Glands into Skin Grafts
Incorporating encapsulated sweat gland cells into engineered skin tissue produces a more realistic skin graft and may improve patients’ quality of life.
