Contents
Vol 2, Issue 26
Contents
Commentary
- Training Translators for Smart Drug Discovery
Human capital is a rate-limiting constraint in translational medicine and therapeutics.
Perspective
- Rod-Derived Cone Viability Factor for Treating Blinding Diseases: From Clinic to Redox Signaling
A neuroprotective protein may be broadly useful for treating degenerative retinal diseases caused by mutations in a number of different genes.
Research Articles
- Airway PI3K Pathway Activation Is an Early and Reversible Event in Lung Cancer Development
A cancer-associated signaling pathway is reversibly activated in the normal airways of smokers before they develop lung cancer, presenting an opportunity for preventive therapy.
- Klf15 Deficiency Is a Molecular Link Between Heart Failure and Aortic Aneurysm Formation
The co-occurrence of heart failure and aortic aneurysms may be explained by their common dependence on a transcriptional regulator, which now presents a possible therapeutic target.
Editors' Choice
- Mom's Diet and Baby's Appetite
Maternal diet affects the expression of fetal hormones that influence feeding behavior.
- Bladder Relief?
A genome-wide association study identifies a novel variant located near a previously known variant linked to low-grade recurrent bladder cancer.
- Does Cancer Know Which Way Is Up?
Microdeletions in polarity genes occur in a subset of cancers.
- Antibiotic Augmentation of Allografts
A bone graft destined for transplantation can be coated with antibiotics, reducing adherent bacteria and thus the risk of infection to the recipient.
Podcast
- Science Translational Medicine Podcast: 7 April 2010
A conversation about the Commentary published in the 7 April 2010 issue of Science Translational Medicine.
