Research ArticleSepsis

Targeting Robo4-Dependent Slit Signaling to Survive the Cytokine Storm in Sepsis and Influenza

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Science Translational Medicine  17 Mar 2010:
Vol. 2, Issue 23, pp. 23ra19
DOI: 10.1126/scitranslmed.3000678

Article Information

vol. 2 no. 23 23ra19

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received November 25, 2009
  • Accepted February 26, 2010
  • .

Author Information

  1. Nyall R. London1,2,3,*,
  2. Weiquan Zhu1,2,3,*,
  3. Fernando A. Bozza4,
  4. Matthew C. P. Smith1,2,3,
  5. Daniel M. Greif5,6,
  6. Lise K. Sorensen1,2,3,
  7. Luming Chen1,2,3,
  8. Yuuki Kaminoh1,2,3,
  9. Aubrey C. Chan1,2,3,
  10. Samuel F. Passi1,2,3,
  11. Craig W. Day7,
  12. Dale L. Barnard7,
  13. Guy A. Zimmerman2,
  14. Mark A. Krasnow5 and
  15. Dean Y. Li1,2,3,
  1. 1Department of Oncological Sciences, University of Utah, Salt Lake City, UT 84112, USA.
  2. 2Department of Medicine, University of Utah, Salt Lake City, UT 84112, USA.
  3. 3Program in Molecular Medicine, University of Utah, Salt Lake City, UT 84112, USA.
  4. 4Intensive Care Unit, Instituto de Pesquisa Clínica Evandro Chagas, and Laboratório de Imunofarmacologia, Fundação Oswaldo Cruz, Rio de Janeiro 21045-900, Brazil.
  5. 5Department of Biochemistry and Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.
  6. 6Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
  7. 7Institute for Antiviral Research, Utah State University, Logan, UT 84322, USA.
  1. To whom correspondence should be addressed. E-mail: dean.li{at}u2m2.utah.edu

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