Cancer Sequencing Gets a Little More Personal

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Science Translational Medicine  24 Feb 2010:
Vol. 2, Issue 20, pp. 20ps8
DOI: 10.1126/scitranslmed.3000929

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In this Perspective, we discuss a paper in this issue of Science Translational Medicine, in which Leary and colleagues present a new method based on massive, parallel, and near-complete sequencing of individual tumor genomes. Their findings support the notion that cancer genomes house a spectrum of genetic alterations, many of which are unique to the individual tumor. More validation and a reduction in cost are required for this approach to become common in clinics.


  • Citation: L. Prokunina-Olsson and S. J. Chanock, Cancer sequencing gets a little more personal. Sci. Transl. Med. 2, 20ps8 (2010).

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