Contents
Vol 2, Issue 18
Contents
Commentary
- Liberating Health Data for Clinical Research Applications
Advances in communication and information technology infrastructure and policies to support exchange of health information are providing new opportunities for enhancing clinical research.
Perspective
- Genetic Polymorphisms: A Cornerstone of Translational Biobehavioral Research
A new generation of interdisciplinary research seeks to use common functional genetic polymorphisms to model variability in brain chemistry that regulates behaviorally relevant brain structures and their functions.
Research Article
- A Monoclonal Antibody Against αVβ3 Integrin Inhibits Development of Atherosclerotic Lesions in Diabetic Pigs
An antibody directed at the C terminus of an integrin subunit can prevent the formation of atherosclerotic lesions in diabetic pigs.
Reports
- The Origins of Sexually Transmitted HIV Among Men Who Have Sex with Men
Cell-free virus in seminal plasma is the origin of sexually transmitted HIV among men who have sex with men.
Editors' Choice
- Methylation Balancing Act
Modulators of DNA methylation play a key role in the self-renewal of mammalian tissues.
- Like a Bridge over Troubled Waters: Innervation Changes in the Malfunctioning Heart
Heart failure causes cardiac nerves to change the neurotransmitter they release, potentially protecting the heart.
- Blunted Memories: Time for Decaf?
A new study suggests that adenosine receptor agents such as caffeine may enhance the effects of cannabis on neural signaling.
- A Preemptive Strike Against Resistant Tumor Cells
A few cells within a tumor carry drug-resistance mutations even before treatment is initiated, providing an opportunity to squelch them early.
