27 January 2010
Vol 2, Issue 16
  • Contents

    • Commentary

      • Transforming Medicine via Digital Innovation

        The newfound ability to monitor physiological metrics digitally via non-invasive wireless sensors, along with genome-wide scanning and whole-genome sequencing, should lead to an extraordinary accrual of physiological and biological data about individuals.

    • Perspective

      • Pathogen Microevolution in High Resolution

        The application of next-generation high-throughput genotyping technologies, as illustrated in a recent analysis of a highly resistant Staphylococcus aureus strain, can provide new clues on the geographical origin and intrahospital spread of important microbial pathogens.

    • Research Articles

    • Editors' Choice

      • DAMD to Do Better!

        DAMD, a high-throughput platform for assessing DNA methylation changes, provides new insights into the development and treatment of pediatric brain tumors.

      • Which Came First?

        Researchers use Mendelian randomization to decipher directions of causality between obesity and inflammation.

      • Obesity and Inflammation: The Fas Connection

        The death receptor Fas may contribute to obesity-induced inflammation and the pathogenesis of type 2 diabetes mellitus.

About The Cover

Cover image expansion

ONLINE COVER An App for That. Innovations in wireless medical technologies permit real-time data about a patient's vital signs to be delivered directly to a doctor's smart phone, allowing remote continuous monitoring. In this issue, Topol discusses how advances in digital medicine—in genomics and wireless technologies—may change the future and flavor of health care. [CREDIT: IMAGE COURTESY OF AIRSTRIP TECHNOLOGIES]