Meeting the Governance Challenges of Next-Generation Biorepository Research

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Science Translational Medicine  20 Jan 2010:
Vol. 2, Issue 15, pp. 15cm3
DOI: 10.1126/scitranslmed.3000361


Advances in clinical translational research have led to an explosion of interest in infrastructure development and data sharing facilitated by biorepositories of specimens and linked health information. These efforts are qualitatively different from the single-center sample collections that preceded them and pose substantial new ethics and regulatory challenges for investigators and institutions. New research governance approaches, which can address current and anticipated challenges, promote high-quality research, and provide a robust basis for ongoing research participation, are urgently required.


  • Citation: S. M. Fullerton, N. R. Anderson, G. Guzauskas, D. Freeman, K. Fryer-Edwards, Meeting the governance challenges of next-generation biorepository research. Sci. Transl. Med. 2, 15cm3 (2010).

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