31 March 2021
Vol 13, Issue 587

About The Cover

Cover image expansion

ONLINE COVER Capturing Chloride Concentrations, No Sweat. This stylized image shows an epidermal microfluidic sweat sensor on the forearm of a person. Ray et al. developed flexible, adhesive sensors that could capture and quantify chloride concentration in sweat. The sweat sensors provided a colorimetric readout and could be analyzed in situ using a smartphone. Testing in patients with cystic fibrosis, who have elevated sweat chloride, showed similar results to standard sweat collection methods, with fewer occurrences of insufficient sweat volume collection. These sweat stickers could be applied to patients of different ages to noninvasively diagnose or monitor cystic fibrosis. [CREDIT: TYLER R. RAY/SCIENCE TRANSLATIONAL MEDICINE]