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Research ArticlePain
Long-lasting analgesia via targeted in situ repression of NaV1.7 in mice
- View ORCID ProfileAna M. Moreno1,*,
- View ORCID ProfileFernando Alemán1,*,
- View ORCID ProfileGlaucilene F. Catroli2,
- View ORCID ProfileMatthew Hunt2,
- View ORCID ProfileMichael Hu1,
- View ORCID ProfileAmir Dailamy1,
- Andrew Pla1,
- View ORCID ProfileSarah A. Woller2,†,
- View ORCID ProfileNathan Palmer3,
- View ORCID ProfileUdit Parekh4,
- Daniella McDonald1,5,
- View ORCID ProfileAmanda J. Roberts6,
- Vanessa Goodwill7,
- View ORCID ProfileIan Dryden7,
- View ORCID ProfileRobert F. Hevner7,
- View ORCID ProfileLauriane Delay2,
- View ORCID ProfileGilson Gonçalves dos Santos2,
- View ORCID ProfileTony L. Yaksh2,‡ and
- View ORCID ProfilePrashant Mali1,‡
- 1Department of Bioengineering, University of California San Diego, San Diego, CA 92093, USA.
- 2Department of Anesthesiology, University of California San Diego, San Diego, CA 92093, USA.
- 3Division of Biological Sciences, University of California San Diego , San Diego, CA 92093, USA.
- 4Department of Electrical Engineering, University of California San Diego , San Diego, CA 92093, USA.
- 5Biomedical Sciences Graduate Program, University of California San Diego, San Diego, San Diego, CA 92093, USA.
- 6Animal Models Core, Scripps Research Institute, La Jolla, CA 92037, USA.
- 7Department of Neuropathology, University of California San Diego, San Diego, CA 92093, USA.
- ↵‡Corresponding author. Email: pmali{at}ucsd.edu (P.M.); tyaksh{at}ucsd.edu (T.L.Y.)
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Science Translational Medicine 10 Mar 2021:
Vol. 13, Issue 584, eaay9056
DOI: 10.1126/scitranslmed.aay9056
Vol. 13, Issue 584, eaay9056
DOI: 10.1126/scitranslmed.aay9056
Ana M. Moreno
1Department of Bioengineering, University of California San Diego, San Diego, CA 92093, USA.
Fernando Alemán
1Department of Bioengineering, University of California San Diego, San Diego, CA 92093, USA.
Glaucilene F. Catroli
2Department of Anesthesiology, University of California San Diego, San Diego, CA 92093, USA.
Matthew Hunt
2Department of Anesthesiology, University of California San Diego, San Diego, CA 92093, USA.
Michael Hu
1Department of Bioengineering, University of California San Diego, San Diego, CA 92093, USA.
Amir Dailamy
1Department of Bioengineering, University of California San Diego, San Diego, CA 92093, USA.
Andrew Pla
1Department of Bioengineering, University of California San Diego, San Diego, CA 92093, USA.
Sarah A. Woller
2Department of Anesthesiology, University of California San Diego, San Diego, CA 92093, USA.
Nathan Palmer
3Division of Biological Sciences, University of California San Diego , San Diego, CA 92093, USA.
Udit Parekh
4Department of Electrical Engineering, University of California San Diego , San Diego, CA 92093, USA.
Daniella McDonald
1Department of Bioengineering, University of California San Diego, San Diego, CA 92093, USA.
5Biomedical Sciences Graduate Program, University of California San Diego, San Diego, San Diego, CA 92093, USA.
Amanda J. Roberts
6Animal Models Core, Scripps Research Institute, La Jolla, CA 92037, USA.
Vanessa Goodwill
7Department of Neuropathology, University of California San Diego, San Diego, CA 92093, USA.
Ian Dryden
7Department of Neuropathology, University of California San Diego, San Diego, CA 92093, USA.
Robert F. Hevner
7Department of Neuropathology, University of California San Diego, San Diego, CA 92093, USA.
Lauriane Delay
2Department of Anesthesiology, University of California San Diego, San Diego, CA 92093, USA.
Gilson Gonçalves dos Santos
2Department of Anesthesiology, University of California San Diego, San Diego, CA 92093, USA.
Tony L. Yaksh
2Department of Anesthesiology, University of California San Diego, San Diego, CA 92093, USA.
Prashant Mali
1Department of Bioengineering, University of California San Diego, San Diego, CA 92093, USA.
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