10 February 2021
Vol 13, Issue 580

About The Cover

Cover image expansion

ONLINE COVER Locoregional Liquid Ablation. This illustration shows a liquid ablation agent being injected into a tumor in the liver under ultrasound imaging guidance. Albadawi et al. developed an injectable ionic liquid that killed tumor cells in rat hepatocellular carcinoma and rabbit hepatic tumor models. The agent also ablated tumors when injected into resected human tumor tissue ex vivo and enabled uniform distribution of co-injected dyes or chemotherapeutics. Use of this liquid ablation agent as a locoregional therapy could help bridge patients with hepatocellular carcinoma to liver transplant. [CREDIT: MIKE AUSTIN/INTERNAL ART MEDICAL ILLUSTRATION]