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Morphine acts on spinal dynorphin neurons to cause itch through disinhibition

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Science Translational Medicine  03 Feb 2021:
Vol. 13, Issue 579, eabc3774
DOI: 10.1126/scitranslmed.abc3774

Article Information

vol. 13 no. 579

PubMed: 
Print ISSN: 
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History: 
  • Received for publication April 21, 2020
  • Accepted for publication August 13, 2020
  • .

Author Information

  1. Eileen Nguyen1,2,
  2. Grace Lim3,4,
  3. Huiping Ding5,
  4. Junichi Hachisuka1,6,
  5. Mei-Chuan Ko5 and
  6. Sarah E. Ross1,*
  1. 1Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
  2. 2Medical Scientist Training Program, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
  3. 3Department of Anesthesiology and Perioperative Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  4. 4Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  5. 5Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.
  6. 6Institute of Neuroscience and Psychology, University of Glasgow, Glasgow, UK.
  1. *Corresponding author. Email: saross{at}pitt.edu

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