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A chimeric antigen receptor with antigen-independent OX40 signaling mediates potent antitumor activity

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Science Translational Medicine  27 Jan 2021:
Vol. 13, Issue 578, eaba7308
DOI: 10.1126/scitranslmed.aba7308

Article Information

vol. 13 no. 578

PubMed: 
Print ISSN: 
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History: 
  • Received for publication January 1, 2020
  • Resubmitted August 24, 2020
  • Accepted for publication November 20, 2020
  • .

Author Information

  1. Huihui Zhang1,2,3,*,
  2. Fanlin Li1,2,3,*,
  3. Jiang Cao4,*,
  4. Xin Wang5,
  5. Hai Cheng4,
  6. Kunming Qi4,
  7. Gang Wang6,
  8. Kailin Xu4,
  9. Junnian Zheng6,
  10. Yang-Xin Fu7 and
  11. Xuanming Yang1,2,3,
  1. 1Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.
  2. 2Joint International Research Laboratory of Metabolic and Developmental Sciences, Shanghai Jiao Tong University, Shanghai 200240, China.
  3. 3Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai 200240, China.
  4. 4Department of Hematology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, China.
  5. 5Shanghai Longyao Biotechnology Limited, Shanghai 201203, China.
  6. 6Cancer Institute, Xuzhou Medical University, Xuzhou 221002, China.
  7. 7Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  1. Corresponding author. Email: xuanmingyang{at}sjtu.edu.cn
  • * These authors contributed equally to this work.

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Mar 2021986198174
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May 20215218090
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