Editors' ChoiceCancer

Unconventional interleukin-1β release suppresses antitumor immunity

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Science Translational Medicine  20 Jan 2021:
Vol. 13, Issue 577, eabg4726
DOI: 10.1126/scitranslmed.abg4726

Abstract

Inflammasome-independent release of IL-1β in the tumor microenvironment recruits T cell–suppressive neutrophils that support cancer progression.

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