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Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide

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Science Translational Medicine  06 Jan 2021:
Vol. 13, Issue 575, eabb6295
DOI: 10.1126/scitranslmed.abb6295

Article Information

vol. 13 no. 575

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication March 8, 2020
  • Resubmitted August 19, 2020
  • Accepted for publication September 30, 2020
  • .

Author Information

  1. Max Jan1,2,3,
  2. Irene Scarfò4,5,
  3. Rebecca C. Larson4,5,
  4. Amanda Walker1,2,6,
  5. Andrea Schmidts4,5,
  6. Andrew A. Guirguis1,2,
  7. Jessica A. Gasser1,2,
  8. Mikołaj Słabicki1,2,
  9. Amanda A. Bouffard4,5,
  10. Ana P. Castano4,5,
  11. Michael C. Kann4,5,
  12. Maria L. Cabral4,5,
  13. Alexander Tepper1,2,
  14. Daniel E. Grinshpun1,2,
  15. Adam S. Sperling1,2,
  16. Taeyoon Kyung7,
  17. Quinlan L. Sievers1,
  18. Michael E. Birnbaum7,
  19. Marcela V. Maus1,4,5,*, and
  20. Benjamin L. Ebert1,2,8,*,
  1. 1Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.
  2. 2Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  3. 3Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA.
  4. 4Cellular Immunotherapy Program, Massachusetts General Hospital Cancer Center, Charlestown, MA 02114, USA.
  5. 5Harvard Medical School, Boston, MA 02115, USA.
  6. 6Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA 19107, USA.
  7. 7Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
  8. 8Howard Hughes Medical Institute, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  1. Corresponding author. Email: mvmaus{at}mgh.harvard.edu (M.V.M.); benjamin_ebert{at}dfci.harvard.edu (B.L.E.)
  • * These authors contributed equally to this work.

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Article usage: January 2021 to April 2021

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Feb 20212026315343
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