FocusAlzheimer’s Disease

Endosomal recycling reconciles the Alzheimer’s disease paradox

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Science Translational Medicine  02 Dec 2020:
Vol. 12, Issue 572, eabb1717
DOI: 10.1126/scitranslmed.abb1717

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Abstract

A hub-and-spoke model with endosomal recycling as the hub can reconcile the pathogenic contribution of amyloid precursor protein to Alzheimer’s disease.

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