Research ArticleCancer

Antitumor activity without on-target off-tumor toxicity of GD2–chimeric antigen receptor T cells in patients with neuroblastoma

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Science Translational Medicine  25 Nov 2020:
Vol. 12, Issue 571, eabd6169
DOI: 10.1126/scitranslmed.abd6169

Article Information

vol. 12 no. 571

Print ISSN: 
Online ISSN: 
History: 
  • Received for publication July 7, 2020
  • Accepted for publication September 23, 2020
  • .

Author Information

  1. Karin Straathof1,2,
  2. Barry Flutter1,2,
  3. Rebecca Wallace1,2,
  4. Neha Jain2,
  5. Thalia Loka2,
  6. Sarita Depani2,
  7. Gary Wright2,
  8. Simon Thomas3,4,
  9. Gordon Weng-Kit Cheung3,
  10. Talia Gileadi1,
  11. Sian Stafford1,
  12. Evangelia Kokalaki3,
  13. Jack Barton1,
  14. Clare Marriott2,
  15. Dyanne Rampling2,
  16. Olumide Ogunbiyi2,
  17. Ayse U. Akarca3,
  18. Teresa Marafioti3,
  19. Sarah Inglott2,
  20. Kimberly Gilmour2,
  21. Muhammad Al-Hajj4,
  22. William Day4,
  23. Kieran McHugh2,
  24. Lorenzo Biassoni2,
  25. Natalie Sizer2,
  26. Claire Barton5,
  27. David Edwards5,
  28. Ilaria Dragoni5,
  29. Julie Silvester5,
  30. Karen Dyer5,
  31. Stephanie Traub5,
  32. Lily Elson5,
  33. Sue Brook5,
  34. Nigel Westwood5,
  35. Lesley Robson5,
  36. Ami Bedi2,
  37. Karen Howe2,
  38. Ailish Barry2,
  39. Catriona Duncan2,
  40. Giuseppe Barone2,
  41. Martin Pule3,* and
  42. John Anderson1,2,*
  1. 1Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 1EH, UK.
  2. 2Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 3JH, UK.
  3. 3UCL Cancer Institute, London WC1E 6DD, UK.
  4. 4Autolus Ltd., London W12 7FP, UK.
  5. 5Centre for Drug Development, Cancer Research UK, London E20 1JQ, UK.
  1. *Corresponding author. Email: m.pule{at}ucl.ac.uk (M.P.); j.anderson{at}ucl.ac.uk (J.A.)

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Nov 202021453721176
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Mar 202153813678
Apr 202145010955
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