Research ArticleAlzheimer’s Disease

Gga3 deletion and a GGA3 rare variant associated with late onset Alzheimer’s disease trigger BACE1 accumulation in axonal swellings

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Science Translational Medicine  18 Nov 2020:
Vol. 12, Issue 570, eaba1871
DOI: 10.1126/scitranslmed.aba1871

Article Information

vol. 12 no. 570

PubMed: 
Print ISSN: 
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History: 
  • Received for publication November 14, 2019
  • Resubmitted May 18, 2020
  • Accepted for publication August 3, 2020
  • .

Author Information

  1. Selene Lomoio1,
  2. Rachel Willen1,
  3. WonHee Kim1,
  4. Kevin Z. Ho1,
  5. Edward K. Robinson1,
  6. Dmitry Prokopenko2,
  7. Matthew E. Kennedy3,
  8. Rudolph E. Tanzi2 and
  9. Giuseppina Tesco1,*
  1. 1Department of Neuroscience, Tufts University School of Medicine, Boston, MA 02111, USA.
  2. 2Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
  3. 3Department of Neuroscience, Merck & Co. Inc., Boston, MA 02115, USA.
  1. *Corresponding author. Email: giuseppina.tesco{at}tufts.edu

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Dec 2020585335177
Jan 202126610067
Feb 20213364941
Mar 20212785236
Apr 2021215198

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