Research ArticleVaccines

Antibody binding to native cytomegalovirus glycoprotein B predicts efficacy of the gB/MF59 vaccine in humans

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Science Translational Medicine  04 Nov 2020:
Vol. 12, Issue 568, eabb3611
DOI: 10.1126/scitranslmed.abb3611

Article Information

vol. 12 no. 568

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication February 18, 2020
  • Accepted for publication June 2, 2020
  • .

Author Information

  1. Jennifer A. Jenks1,
  2. Cody S. Nelson1,2,
  3. Hunter K. Roark1,
  4. Matthew L. Goodwin1,
  5. Robert F. Pass3,
  6. David I. Bernstein4,
  7. Emmanuel B. Walter1,
  8. Kathryn M. Edwards5,
  9. Dai Wang6,
  10. Tong-Ming Fu7,
  11. Zhiqiang An7,
  12. Cliburn Chan8,* and
  13. Sallie R. Permar1,9,*,
  1. 1Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC 27705, USA.
  2. 2Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
  3. 3Department of Pediatrics, University of Alabama of Birmingham, Birmingham, AL 35233, USA.
  4. 4Department of Pediatrics, Cincinnati Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229, USA.
  5. 5Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  6. 6Merck & Co. Inc., Kenilworth, NJ 07033, USA.
  7. 7Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center, Houston, TX 77030, USA.
  8. 8Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC 27705, USA.
  9. 9Department of Pediatrics, Duke University Medical Center, Durham, NC 27705, USA.
  1. Corresponding author. Email: sallie.permar{at}duke.edu
  • * These authors contributed equally to this work.

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