Research ArticleMICROBIOTA

Disturbed gut microbiota and bile homeostasis in Giardia-infected mice contributes to metabolic dysregulation and growth impairment

See allHide authors and affiliations

Science Translational Medicine  14 Oct 2020:
Vol. 12, Issue 565, eaay7019
DOI: 10.1126/scitranslmed.aay7019

Article Information

vol. 12 no. 565

Print ISSN: 
Online ISSN: 
  • Received for publication July 11, 2019
  • Resubmitted January 6, 2020
  • Accepted for publication May 11, 2020
  • .

Author Information

  1. Ambre Riba1,
  2. Kasra Hassani2,
  3. Alesia Walker3,
  4. Niels van Best1,4,
  5. Dunja von Zeschwitz1,
  6. Teresa Anslinger1,
  7. Nina Sillner3,5,
  8. Stefanie Rosenhain6,
  9. Daniel Eibach7,
  10. Oumou Maiga-Ascofaré8,
  11. Ulrike Rolle-Kampczyk9,
  12. Marijana Basic10,
  13. Anne Binz11,
  14. Sabine Mocek12,
  15. Beate Sodeik11,
  16. Rudolf Bauerfeind13,
  17. Antje Mohs14,
  18. Christian Trautwein14,
  19. Fabian Kiessling6,15,16,
  20. Jürgen May7,
  21. Martin Klingenspor12,
  22. Felix Gremse6,17,18,
  23. Philippe Schmitt-Kopplin3,5,19,
  24. André Bleich10,
  25. Natalia Torow1,
  26. Martin von Bergen9,20 and
  27. Mathias W. Hornef1,*
  1. 1Institute of Medical Microbiology, RWTH University Hospital, 52074 Aachen, Germany.
  2. 2Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, 30625 Hannover, Germany.
  3. 3Research Unit Analytical BioGeoChemistry, Helmholtz Zentrum München, 85764 Neuherberg, Germany.
  4. 4Department of Medical Microbiology and NUTRIM, Maastricht University, Maastricht, Netherlands.
  5. 5ZIEL Institute for Food and Health, Technical University of Munich, 85354 Freising, Germany.
  6. 6Institute for Experimental Molecular Imaging, University Hospital Aachen, 52074 Aachen, Germany.
  7. 7Department of Infectious Disease Epidemiology, Bernhard Nocht Institute for Tropical Medicine, 20359 Hamburg, Germany.
  8. 8Kumasi Centre for Collaborative Research in Tropical Medicine, Kumasi, Ghana.
  9. 9Helmholtz Centre for Environmental Research, Department of Molecular Systems Biology, 04318 Leipzig, Germany.
  10. 10Institute for Laboratory Animal Science, Hannover Medical School, 30625 Hannover, Germany.
  11. 11Institute of Virology, Hannover Medical School, 30625 Hannover, Germany.
  12. 12Chair for Molecular Nutritional Medicine, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
  13. 13Research Core Unit for Laser Microscopy, Hannover Medical School, 30625 Hannover, Germany.
  14. 14Medizinische Klinik III, RWTH University Hospital, Aachen, 52074 Aachen, Germany.
  15. 15Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
  16. 16Fraunhofer Institute for Digital Medicine MEVIS, Bremen, Germany.
  17. 17Software Tools for Computational Engineering, RWTH Aachen University, 52072 Aachen, Germany.
  18. 18Gremse-IT GmbH, 52068 Aachen, Germany.
  19. 19Analytical Food Chemistry, Technical University of Munich, 85354 Freising, Germany.
  20. 20Institute of Biochemistry, Faculty of Life Sciences, University of Leipzig, Bruderstrase 34, D-04103 Leipzig, Germany.
  1. *Corresponding author. Email: mhornef{at}


Article usage

Article usage: October 2020 to October 2020

Oct 20202590668209

Stay Connected to Science Translational Medicine