Research ArticleCORONAVIRUS
Immune responses to SARS-CoV-2 infection in hospitalized pediatric and adult patients
- View ORCID ProfileCarl A. Pierce1,
- Paula Preston-Hurlburt2,
- Yile Dai2,
- View ORCID ProfileClare Burn Aschner1,*,
- View ORCID ProfileNatalia Cheshenko3,
- View ORCID ProfileBenjamin Galen4,
- View ORCID ProfileScott J. Garforth5,
- View ORCID ProfileNatalia G. Herrera5,
- View ORCID ProfileRohit K. Jangra1,
- View ORCID ProfileNicholas C. Morano5,
- View ORCID ProfileErika Orner6,
- View ORCID ProfileSharlene Sy3,
- View ORCID ProfileKartik Chandran1,
- View ORCID ProfileJames Dziura7,
- Steven C. Almo5,
- View ORCID ProfileAaron Ring2,
- View ORCID ProfileMarla J. Keller4,
- View ORCID ProfileKevan C. Herold2,7,†,‡ and
- View ORCID ProfileBetsy C. Herold1,3,†,‡
- 1Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
- 2Department of Immunobiology, Yale University, New Haven, CT 06520, USA.
- 3Department of Pediatrics, The Children’s Hospital at Montefiore and Albert Einstein College of Medicine, Bronx, NY 10461, USA.
- 4Department of Medicine, Montefiore Medical Center, Bronx, NY 10467, USA.
- 5Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
- 6Department of Pathology, Montefiore Medical Center, Bronx, NY 10467, USA.
- 7Department of Emergency Medicine and Biostatistics, Yale University, New Haven, CT 06520, USA.
- 8Department of Internal Medicine, Yale University, New Haven, CT 06520, USA.
- ↵†Corresponding author. Email: kevan.herold{at}yale.edu (K.C.H.); betsy.herold{at}einstein.yu.edu (B.C.H.)
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Science Translational Medicine 07 Oct 2020:
Vol. 12, Issue 564, eabd5487
DOI: 10.1126/scitranslmed.abd5487
Vol. 12, Issue 564, eabd5487
DOI: 10.1126/scitranslmed.abd5487
Carl A. Pierce
1Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Paula Preston-Hurlburt
2Department of Immunobiology, Yale University, New Haven, CT 06520, USA.
Yile Dai
2Department of Immunobiology, Yale University, New Haven, CT 06520, USA.
Clare Burn Aschner
1Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Natalia Cheshenko
3Department of Pediatrics, The Children’s Hospital at Montefiore and Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Benjamin Galen
4Department of Medicine, Montefiore Medical Center, Bronx, NY 10467, USA.
Scott J. Garforth
5Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Natalia G. Herrera
5Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Rohit K. Jangra
1Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Nicholas C. Morano
5Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Erika Orner
6Department of Pathology, Montefiore Medical Center, Bronx, NY 10467, USA.
Sharlene Sy
3Department of Pediatrics, The Children’s Hospital at Montefiore and Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Kartik Chandran
1Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
James Dziura
7Department of Emergency Medicine and Biostatistics, Yale University, New Haven, CT 06520, USA.
Steven C. Almo
5Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Aaron Ring
2Department of Immunobiology, Yale University, New Haven, CT 06520, USA.
Marla J. Keller
4Department of Medicine, Montefiore Medical Center, Bronx, NY 10467, USA.
Kevan C. Herold
2Department of Immunobiology, Yale University, New Haven, CT 06520, USA.
7Department of Emergency Medicine and Biostatistics, Yale University, New Haven, CT 06520, USA.
Betsy C. Herold
1Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
3Department of Pediatrics, The Children’s Hospital at Montefiore and Albert Einstein College of Medicine, Bronx, NY 10461, USA.