Editors' ChoiceAlzheimer’s Disease

Leaky pipes: Tau and apoE implicated in blood-brain barrier dysfunction in Alzheimer disease

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Science Translational Medicine  09 Sep 2020:
Vol. 12, Issue 560, eabe1710
DOI: 10.1126/scitranslmed.abe1710

Abstract

Concentrations of tight junction proteins correlate with tau and apolipoprotein E in Alzheimer disease brain tissue independent of cerebral amyloid angiopathy.

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