Research ArticleCancer

A YAP/FOXM1 axis mediates EMT-associated EGFR inhibitor resistance and increased expression of spindle assembly checkpoint components

See allHide authors and affiliations

Science Translational Medicine  02 Sep 2020:
Vol. 12, Issue 559, eaaz4589
DOI: 10.1126/scitranslmed.aaz4589

Article Information

vol. 12 no. 559

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication September 13, 2019
  • Resubmitted May 5, 2020
  • Accepted for publication July 17, 2020
  • .

Author Information

  1. Monique B. Nilsson1,
  2. Huiying Sun1,
  3. Jacqulyne Robichaux1,
  4. Matthias Pfeifer2,
  5. Ultan McDermott2,
  6. Jon Travers2,
  7. Lixia Diao3,
  8. Yuanxin Xi3,
  9. Pan Tong3,
  10. Li Shen3,
  11. Mia Hofstad1,*,
  12. Masanori Kawakami1,,
  13. Xiuning Le1,
  14. Xi Liu1,,
  15. Youhong Fan1,
  16. Alissa Poteete1,
  17. Limei Hu1,
  18. Marcelo V. Negrao1,
  19. Hai Tran1,
  20. Ethan Dmitrovsky1,,
  21. David Peng1,§,
  22. Don L. Gibbons1,
  23. Jing Wang3 and
  24. John V. Heymach1,||
  1. 1Departments of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  2. 2Oncology R&D, AstraZeneca, Cambridge, CB2 0RE, UK.
  3. 3Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  1. ||Corresponding author. Email: jheymach{at}mdanderson.org
  • * Present address: University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

  • Present address: University of Tokyo Graduate School of Medicine, Tokyo 113-8654, Japan.

  • Present address: Frederick National Laboratory for Cancer Research, Frederick, MD 21701, USA.

  • § Present address: New York University Langone Medical Center, New York, NY 10016, USA.

Altmetric

Article usage

Article usage: August 2020 to April 2021

AbstractFullPdf
Aug 2020001
Sep 202039501476595
Oct 2020216133111
Nov 20202397470
Dec 20201618974
Jan 20211557786
Feb 20211398376
Mar 2021995649
Apr 20211172518

Stay Connected to Science Translational Medicine