Research ArticleVASCULAR SURGERY

Artery to vein configuration of arteriovenous fistula improves hemodynamics to increase maturation and patency

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Science Translational Medicine  19 Aug 2020:
Vol. 12, Issue 557, eaax7613
DOI: 10.1126/scitranslmed.aax7613

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Favorable fistulae

Patients with end-stage kidney disease require surgery to create arteriovenous fistulae (AVF) for dialysis access. Bai et al. investigated whether an artery-to-vein (A-V) configuration using radial artery deviation and reimplantation improved maturity and patency of AVF. They saw decreased hyperplasia and improved hemodynamics in A-V–configured AVF in rats and longer-term patency with reduced reintervention rates in patients. Results support the use of A-V–configured AVF for durable hemodialysis access.

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