Research ArticleMultiple Sclerosis

Reelin depletion protects against autoimmune encephalomyelitis by decreasing vascular adhesion of leukocytes

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Science Translational Medicine  12 Aug 2020:
Vol. 12, Issue 556, eaay7675
DOI: 10.1126/scitranslmed.aay7675

Article Information

vol. 12 no. 556

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication July 17, 2019
  • Resubmitted February 21, 2020
  • Accepted for publication June 5, 2020
  • .

Author Information

  1. Laurent Calvier1,2,*,
  2. Guillaume Demuth1,2,
  3. Navid Manouchehri3,
  4. Connie Wong1,2,
  5. Anastasia Sacharidou4,
  6. Chieko Mineo4,
  7. Philip W. Shaul4,
  8. Nancy L. Monson3,
  9. Maria Z. Kounnas5,
  10. Olaf Stüve3,6 and
  11. Joachim Herz1,2,3,7,*
  1. 1Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  2. 2Center for Translational Neurodegeneration Research, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  3. 3Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  4. 4Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  5. 5Reelin Therapeutics Inc. La Jolla, CA 92037, USA.
  6. 6Department of Neurology, VA North Texas Health Care System, Medical Service, Dallas, TX 75390, USA.
  7. 7Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  1. *Corresponding author. Email: calvier.laurent{at}gmail.com (L.C.); joachim.herz{at}utsouthwestern.edu (J.H.)

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