12 August 2020
Vol 12, Issue 556

About The Cover

Cover image expansion

ONLINE COVER A Box Set to Treat Cancer. The boxes in this image are microfabricated particles, ready to be loaded with a stimulator of interferon gene (STING) agonist for anticancer immunotherapy. STING agonists require repeated intratumoral injections over the course of months, which are unpleasant for patients at best and not possible when tumors are located in deep organs. Lu et al. engineered microparticles to release doses of STING agonist at different time intervals such that a single injection or implantation of particles provides a complete course of treatment. [CREDIT: XUEGUANG LU, ZACHARY TOCHKA]