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A rapidly deployable individualized system for augmenting ventilator capacity
- View ORCID ProfileShriya S. Srinivasan1,2,3,
- View ORCID ProfileKhalil B. Ramadi1,2,3,
- View ORCID ProfileFrancesco Vicario4,
- Declan Gwynne1,2,3,
- View ORCID ProfileAlison Hayward2,3,5,
- View ORCID ProfileDavid Lagier6,
- View ORCID ProfileRobert Langer1,3,7,8,
- View ORCID ProfileJoseph J. Frassica4,8,
- Rebecca M. Baron9 and
- View ORCID ProfileGiovanni Traverso1,2,3,*
- 1Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
- 2Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
- 3David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
- 4Philips Research North America, Cambridge, MA 02141, USA.
- 5Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
- 6Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02139, USA.
- 7Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
- 8Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
- 9Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
- ↵*Corresponding author. Email: cgt20{at}mit.edu, ctraverso{at}bwh.harvard.edu
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Science Translational Medicine 24 Jun 2020:
Vol. 12, Issue 549, eabb9401
DOI: 10.1126/scitranslmed.abb9401
Vol. 12, Issue 549, eabb9401
DOI: 10.1126/scitranslmed.abb9401
Shriya S. Srinivasan
1Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
2Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
3David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Khalil B. Ramadi
1Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
2Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
3David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Francesco Vicario
4Philips Research North America, Cambridge, MA 02141, USA.
Declan Gwynne
1Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
2Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
3David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Alison Hayward
2Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
3David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
5Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
David Lagier
6Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02139, USA.
Robert Langer
1Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
3David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
7Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
8Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Joseph J. Frassica
4Philips Research North America, Cambridge, MA 02141, USA.
8Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Rebecca M. Baron
9Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
Giovanni Traverso
1Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
2Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
3David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
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