Editors' ChoiceCancer

Beware of monocytes bearing gifts

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Science Translational Medicine  20 May 2020:
Vol. 12, Issue 544, eabb7101
DOI: 10.1126/scitranslmed.abb7101

Abstract

Monocytic myeloid-derived suppressor cells accumulate methylglyoxal, which inhibits their metabolic function and can be transferred to CD8+ T cells.

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