Research ArticleMalaria

A double-blind, placebo-controlled phase 1/2a trial of the genetically attenuated malaria vaccine PfSPZ-GA1

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Science Translational Medicine  20 May 2020:
Vol. 12, Issue 544, eaaz5629
DOI: 10.1126/scitranslmed.aaz5629

Article Information

vol. 12 no. 544

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication September 19, 2019
  • Accepted for publication April 22, 2020
  • .

Author Information

  1. Meta Roestenberg1,2,*,
  2. Jona Walk3,4,*,
  3. Saskia C. van der Boor3,,
  4. Marijke C. C. Langenberg1,,
  5. Marie-Astrid Hoogerwerf1,
  6. Jacqueline J. Janse1,
  7. Mikhael Manurung1,
  8. X. Zen Yap3,
  9. Amanda Fabra García3,
  10. Jan Pieter R. Koopman1,
  11. Pauline Meij5,
  12. Els Wessels6,
  13. Karina Teelen3,
  14. Youri M. van Waardenburg3,
  15. Marga van de Vegte-Bolmer3,
  16. Geert Jan van Gemert3,
  17. Leo G. Visser2,
  18. André J. A. M. van der Ven4,
  19. Quirijn de Mast4,
  20. K. C. Natasha7,
  21. Yonas Abebe7,
  22. Tooba Murshedkar7,
  23. Peter F. Billingsley7,
  24. Tom L. Richie7,
  25. B. Kim Lee Sim7,
  26. Chris J. Janse1,
  27. Stephen L. Hoffman7,
  28. Shahid M. Khan1,,§ and
  29. Robert W. Sauerwein3,,||
  1. 1Department of Parasitology, Leiden University Medical Center, 2333 ZA Leiden, Netherlands.
  2. 2Department of Infectious Diseases, Leiden University Medical Center, 2333 ZA Leiden, Netherlands.
  3. 3Radboudumc Center for Infectious Diseases, Department of Medical Microbiology, Radboud University Medical Center, 6525 GA Nijmegen, Netherlands.
  4. 4Radboudumc Center for Infectious Diseases, Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, Netherlands.
  5. 5Interdivisional GMP Facility, Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, 2333 ZA Leiden, Netherlands.
  6. 6Department of Medical Microbiology, Leiden University Medical Center, 2333 ZA Leiden, Netherlands.
  7. 7Sanaria Inc., Rockville, MD 20850, USA.
  1. ||Corresponding author. Email: robert.sauerwein{at}radboudumc.nl
  • * These authors contributed equally to this work.

  • These authors contributed equally to this work.

  • These authors contributed equally to this work.

  • § Deceased.

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