Research ArticleHIV

Vulnerability to reservoir reseeding due to high immune activation after allogeneic hematopoietic stem cell transplantation in individuals with HIV-1

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Science Translational Medicine  06 May 2020:
Vol. 12, Issue 542, eaay9355
DOI: 10.1126/scitranslmed.aay9355

Article Information

vol. 12 no. 542

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication September 11, 2019
  • Accepted for publication April 7, 2020
  • .

Author Information

  1. Johanna M. Eberhard1,2,
  2. Mathieu Angin3,
  3. Caroline Passaes3,
  4. Maria Salgado4,
  5. Valerie Monceaux3,
  6. Elena Knops5,
  7. Guido Kobbe6,
  8. Björn Jensen7,
  9. Maximilian Christopeit8,
  10. Nicolaus Kröger8,
  11. Linos Vandekerckhove9,
  12. Jon Badiola10,
  13. Alessandra Bandera11,
  14. Kavita Raj12,
  15. Jan van Lunzen1,13,
  16. Gero Hütter14,
  17. Jürgen H. E. Kuball15,
  18. Carolina Martinez-Laperche16,
  19. Pascual Balsalobre16,
  20. Mi Kwon16,
  21. José L. Díez-Martín16,
  22. Monique Nijhuis15,
  23. Annemarie Wensing15,
  24. Javier Martinez-Picado4,17,18,
  25. Julian Schulze zur Wiesch1,2,*, and
  26. Asier Sáez-Cirión3,*,
  1. 11. Department of Medicine, Infectious Diseases Unit, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany.
  2. 2DZIF Partner Site (German Center for Infection Research), Hamburg-Lübeck-Borstel-Riems Site, Hamburg, Germany.
  3. 3Institut Pasteur, HIV, Inflammation and Persistence, 75015 Paris, France.
  4. 4AIDS Research Institute IrsiCaixa, 08916 Badalona, Spain.
  5. 5Institute of Virology, University of Cologne, 50935 Cologne, Germany.
  6. 6Department of Haematology, Oncology, and Clinical Immunology, University Hospital Düsseldorf, 40225 Düsseldorf, Germany.
  7. 7Department of Gastroenterology, Hepatology, and Infectious Diseases, University Hospital Düsseldorf, 40225 Düsseldorf, Germany.
  8. 8Department of Stem Cell Transplantation, University Medical Center HamburgEppendorf, 20246 Hamburg, Germany.
  9. 9HIV Cure Research Center, Department of Internal Medicine, Faculty of Medicine and Health Sciences, Ghent University and Ghent University Hospital, B-9000 Ghent, Belgium.
  10. 10Hematology Department, Virgen de las Nieves University Hospital, 18014 Granada, Spain.
  11. 11San Gerardo Hospital, University of Milano-Bicocca, 20900 Monza, Italy.
  12. 12Department of Haematology, King's College Hospital, London SE5 9RS, UK.
  13. 13ViiV Healthcare, Brentford, Middlesex TW8 9GS, UK.
  14. 14Cellex, 01307 Dresden, Germany.
  15. 15University Medical Center Utrecht, 3584 CX, Utrecht, Netherlands.
  16. 16Hospital Universitario Gregorio Marañón, Instituto de Investigación Sanitarias Gregorio Marañón, Universidad Complutense, 28007 Madrid, Spain.
  17. 17UVic-UCC, 08500 Vic, Spain.
  18. 18ICREA, 08010 Barcelona, Spain.
  1. Corresponding author. Email: asier.saez-cirion{at}pasteur.fr (A.S.-C.); julianszw{at}gmail.com (J.S.Z.W.)
  • * These authors contributed equally to this work.

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