Research ArticleInflammation

An anti-inflammatory eicosanoid switch mediates the suppression of type-2 inflammation by helminth larval products

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Science Translational Medicine  22 Apr 2020:
Vol. 12, Issue 540, eaay0605
DOI: 10.1126/scitranslmed.aay0605

Article Information

vol. 12 no. 540

Print ISSN: 
Online ISSN: 
  • Received for publication May 26, 2019
  • Resubmitted November 28, 2019
  • Accepted for publication March 10, 2020
  • .

Author Information

  1. Marta de los Reyes Jiménez1,*,
  2. Antonie Lechner1,*,
  3. Francesca Alessandrini1,
  4. Sina Bohnacker1,
  5. Sonja Schindela1,
  6. Aurélien Trompette2,
  7. Pascal Haimerl1,
  8. Dominique Thomas3,
  9. Fiona Henkel1,
  10. André Mourão4,
  11. Arie Geerlof4,
  12. Clarissa Prazeres da Costa5,
  13. Adam M. Chaker6,
  14. Bernhard Brüne7,
  15. Rolf Nüsing7,
  16. Per-Johan Jakobsson8,
  17. Wolfgang A. Nockher9,
  18. Matthias J. Feige10,
  19. Martin Haslbeck11,
  20. Caspar Ohnmacht1,
  21. Benjamin J. Marsland12,
  22. David Voehringer13,
  23. Nicola L. Harris12,
  24. Carsten B. Schmidt-Weber1,14 and
  25. Julia Esser-von Bieren1,
  1. 1Center of Allergy and Environment (ZAUM), Technical University of Munich and Helmholtz Center Munich, 80802 Munich, Germany.
  2. 2Faculty of Biology and Medicine, University of Lausanne, Service de Pneumologie, Centre Hospitalier Universitaire Vaudois, 1066 Epalinges, Switzerland.
  3. 3Institute of Clinical Pharmacology, Goethe-University Frankfurt, 60590 Frankfurt am Main, Germany.
  4. 4Protein Expression and Purification Facility (PEPF), Institute of Structural Biology, Helmholtz Center Munich, Germany.
  5. 5Institute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich, 81675 Munich, Germany.
  6. 6Department of Otolaryngology, Allergy Section, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.
  7. 7Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt am Main, Germany.
  8. 8Rheumatology Unit, Department of Medicine, Karolinska Institute Stockholm, 171 76 Stockholm, Sweden.
  9. 9Institute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, Philipps-University Marburg, 35043 Marburg, Germany.
  10. 10Center for Integrated Protein Science Munich at the Department of Chemistry and Institute for Advanced Study, Technical University of Munich, 85748 Garching, Germany.
  11. 11Department of Chemistry, Technical University of Munich, 85748 Garching, Germany.
  12. 12Department of Immunology and Pathology, Central Clinical School, Monash University, The Alfred Centre, Melbourne, VIC 3004, Australia.
  13. 13Department of Infection Biology, University Hospital Center, Friedrich-Alexander University, Erlangen-Nuremberg, Germany.
  14. 14Member of the German Center of Lung Research (DZL).
  1. Corresponding author. Email: julia.esser{at}
  • * These authors contributed equally to this work.


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Article usage: April 2020 to May 2021

Apr 202019144681063
May 2020732559312
Jun 20202236842
Jul 20201685846
Aug 20201425645
Sep 20201946537
Oct 20202015441
Nov 20202194817
Dec 20201458533
Jan 20211474729
Feb 20211502812
Mar 20212052213
Apr 20211866430
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