Research ArticleDiabetes

Gene-edited human stem cell–derived β cells from a patient with monogenic diabetes reverse preexisting diabetes in mice

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Science Translational Medicine  22 Apr 2020:
Vol. 12, Issue 540, eaax9106
DOI: 10.1126/scitranslmed.aax9106

Article Information

vol. 12 no. 540

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication May 3, 2019
  • Resubmitted October 11, 2019
  • Accepted for publication March 29, 2020
  • .

Author Information

  1. Kristina G. Maxwell1,2,
  2. Punn Augsornworawat1,2,
  3. Leonardo Velazco-Cruz1,
  4. Michelle H. Kim1,
  5. Rie Asada1,
  6. Nathaniel J. Hogrebe1,
  7. Shuntaro Morikawa1,
  8. Fumihiko Urano1,3,* and
  9. Jeffrey R. Millman1,2,*
  1. 1Division of Endocrinology, Metabolism, and Lipid Research, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA.
  2. 2Department of Biomedical Engineering, Washington University in St. Louis, 1 Brookings Drive, St. Louis, MO 63130, USA.
  3. 3Department of Pathology and Immunology, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA.
  1. *Corresponding author. Email: jmillman{at}wustl.edu (J.R.M.); urano{at}wustl.edu (F.U.)

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