FocusSepsis

Breaking the bond between tetranectin and HMGB1 in sepsis

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Science Translational Medicine  15 Apr 2020:
Vol. 12, Issue 539, eabb2575
DOI: 10.1126/scitranslmed.abb2575

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Abstract

The interaction between tetranectin and high-mobility group box-1 protein may be manipulated via monoclonal antibodies to improve survival in sepsis (Chen et al. same issue).

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