Research ArticleCancer

Urinary detection of lung cancer in mice via noninvasive pulmonary protease profiling

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Science Translational Medicine  01 Apr 2020:
Vol. 12, Issue 537, eaaw0262
DOI: 10.1126/scitranslmed.aaw0262

Article Information

vol. 12 no. 537

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History: 
  • Received for publication December 17, 2018
  • Resubmitted August 6, 2019
  • Accepted for publication March 11, 2020
  • .

Author Information

  1. Jesse D. Kirkpatrick1,2,*,
  2. Andrew D. Warren1,2,*,
  3. Ava P. Soleimany1,2,3,*,
  4. Peter M. K. Westcott1,
  5. Justin C. Voog1,2,4,
  6. Carmen Martin-Alonso1,2,
  7. Heather E. Fleming1,2,
  8. Tuomas Tammela5,
  9. Tyler Jacks1,6 and
  10. Sangeeta N. Bhatia1,2,6,7,8,9,10,
  1. 1Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  2. 2Harvard-MIT Division of Health Sciences and Technology, Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  3. 3Harvard Graduate Program in Biophysics, Harvard University, Boston, MA 02115, USA.
  4. 4Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  5. 5Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  6. 6Howard Hughes Medical Institute, Cambridge, MA 02139, USA.
  7. 7Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  8. 8Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.
  9. 9Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02139, USA.
  10. 10Wyss Institute at Harvard, Boston, MA 02115, USA.
  1. Corresponding author. Email: sbhatia{at}mit.edu
  • * These authors contributed equally to this work.

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