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Platelets from HIV-infected individuals on antiretroviral drug therapy with poor CD4+ T cell recovery can harbor replication-competent HIV despite viral suppression

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Science Translational Medicine  18 Mar 2020:
Vol. 12, Issue 535, eaat6263
DOI: 10.1126/scitranslmed.aat6263

Article Information

vol. 12 no. 535

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication March 20, 2018
  • Resubmitted July 23, 2019
  • Accepted for publication October 1, 2019
  • .

Author Information

  1. Fernando Real1,2,3,
  2. Claude Capron4,
  3. Alexis Sennepin1,2,3,
  4. Riccardo Arrigucci5,
  5. Aiwei Zhu1,2,3,
  6. Gérémy Sannier1,2,3,
  7. Jonathan Zheng1,2,3,
  8. Lin Xu1,2,3,
  9. Jean-Marc Massé2,3,6,
  10. Ségolène Greffe7,
  11. Michelle Cazabat8,
  12. Maribel Donoso9,
  13. Pierre Delobel10,11,12,
  14. Jacques Izopet8,10,11,
  15. Eliseo Eugenin9,
  16. Maria Laura Gennaro5,
  17. Elisabeth Rouveix7,
  18. Elisabeth Cramer Bordé1,2,4 and
  19. Morgane Bomsel1,2,3,*
  1. 1Mucosal Entry of HIV and Mucosal Immunity, Institut Cochin, Université de Paris, Paris, France.
  2. 2INSERM U1016, Paris, France.
  3. 3CNRS UMR8104, Paris, France.
  4. 4Hôpital Ambroise Paré, Boulogne-Billancourt, France.
  5. 5Public Health Research Institute, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, USA.
  6. 6Electron Microscopy Platform, Institut Cochin, Université de Paris, Paris, France.
  7. 7Department of Internal Medicine, Hôpital Ambroise Paré, Boulogne, France.
  8. 8CHU de Toulouse, Hôpital Purpan, Laboratoire de Virologie, Toulouse, France.
  9. 9Department of Neuroscience, Cell Biology, and Anatomy, University of Texas Medical Branch (UTMB), Galveston, TX, USA.
  10. 10INSERM U1043, Toulouse, France.
  11. 11Université Toulouse III Paul-Sabatier, Faculté de Médecine Toulouse-Purpan, Toulouse, France.
  12. 12CHU de Toulouse, Hôpital Purpan, Service des Maladies Infectieuses et Tropicales, Toulouse, France.
  1. *Corresponding author. Email: morgane.bomsel{at}inserm.fr

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