Research ArticleNEUROTECHNOLOGY
A regenerative peripheral nerve interface allows real-time control of an artificial hand in upper limb amputees
- View ORCID ProfilePhilip P. Vu1,
- View ORCID ProfileAlex K. Vaskov2,
- Zachary T. Irwin1,
- View ORCID ProfilePhillip T. Henning3,
- Daniel R. Lueders3,
- Ann T. Laidlaw3,
- View ORCID ProfileAlicia J. Davis4,
- Chrono S. Nu1,
- View ORCID ProfileDeanna H. Gates1,2,5,
- View ORCID ProfileR. Brent Gillespie2,6,
- Stephen W. P. Kemp7,
- Theodore A. Kung7,
- View ORCID ProfileCynthia A. Chestek1,2,8,9,*,† and
- View ORCID ProfilePaul S. Cederna1,7,*,†
- 1Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
- 2Robotics Institute, University of Michigan, Ann Arbor, MI 48109, USA.
- 3Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI 48109, USA.
- 4University of Michigan Hospital Orthotics and Prosthetics Center, Ann Arbor, MI 48109, USA.
- 5School of Kinesiology, University of Michigan, Ann Arbor, MI 48109, USA.
- 6Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
- 7Section of Plastic Surgery, University of Michigan, Ann Arbor, MI 48109, USA.
- 8Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI 48109, USA.
- 9Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI 48109, USA.
- ↵*Corresponding author. Email: cchestek{at}umich.edu (C.A.C.); cederna{at}med.umich.edu (P.S.C.)
↵† These authors contributed equally to this work.
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Science Translational Medicine 04 Mar 2020:
Vol. 12, Issue 533, eaay2857
DOI: 10.1126/scitranslmed.aay2857
Vol. 12, Issue 533, eaay2857
DOI: 10.1126/scitranslmed.aay2857
Philip P. Vu
1Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
Alex K. Vaskov
2Robotics Institute, University of Michigan, Ann Arbor, MI 48109, USA.
Zachary T. Irwin
1Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
Phillip T. Henning
3Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI 48109, USA.
Daniel R. Lueders
3Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI 48109, USA.
Ann T. Laidlaw
3Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI 48109, USA.
Alicia J. Davis
4University of Michigan Hospital Orthotics and Prosthetics Center, Ann Arbor, MI 48109, USA.
Chrono S. Nu
1Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
Deanna H. Gates
1Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
2Robotics Institute, University of Michigan, Ann Arbor, MI 48109, USA.
5School of Kinesiology, University of Michigan, Ann Arbor, MI 48109, USA.
R. Brent Gillespie
2Robotics Institute, University of Michigan, Ann Arbor, MI 48109, USA.
6Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
Stephen W. P. Kemp
7Section of Plastic Surgery, University of Michigan, Ann Arbor, MI 48109, USA.
Theodore A. Kung
7Section of Plastic Surgery, University of Michigan, Ann Arbor, MI 48109, USA.
Cynthia A. Chestek
1Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
2Robotics Institute, University of Michigan, Ann Arbor, MI 48109, USA.
8Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI 48109, USA.
9Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI 48109, USA.
Paul S. Cederna
1Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
7Section of Plastic Surgery, University of Michigan, Ann Arbor, MI 48109, USA.