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Chlorotoxin-directed CAR T cells for specific and effective targeting of glioblastoma

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Science Translational Medicine  04 Mar 2020:
Vol. 12, Issue 533, eaaw2672
DOI: 10.1126/scitranslmed.aaw2672

Article Information

vol. 12 no. 533

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication December 11, 2018
  • Resubmitted November 1, 2019
  • Accepted for publication January 29, 2020
  • .

Author Information

  1. Dongrui Wang1,2,
  2. Renate Starr1,
  3. Wen-Chung Chang1,
  4. Brenda Aguilar1,
  5. Darya Alizadeh1,
  6. Sarah L. Wright1,
  7. Xin Yang1,
  8. Alfonso Brito1,
  9. Aniee Sarkissian1,
  10. Julie R. Ostberg1,
  11. Li Li2,3,
  12. Yanhong Shi3,
  13. Margarita Gutova3,
  14. Karen Aboody3,
  15. Behnam Badie4,
  16. Stephen J. Forman1,*,
  17. Michael E. Barish3,* and
  18. Christine E. Brown1,5,*,
  1. 1Department of Hematology & Hematopoietic Cell Transplantation, City of Hope Medical Center, Duarte, CA 91010, USA.
  2. 2Irell and Manella Graduate School of Biological Sciences, City of Hope Beckman Research Institute, Duarte, CA 91010, USA.
  3. 3Department of Developmental and Stem Cell Biology, City of Hope Beckman Research Institute, Duarte, CA 91010, USA.
  4. 4Division of Neurosurgery, Department of Surgery, City of Hope Medical Center, Duarte, CA 91010, USA.
  5. 5Department of Immuno-Oncology, City of Hope Beckman Research Institute, Duarte, CA 91010, USA.
  1. Corresponding author. Email: cbrown{at}coh.org
  • * These authors contributed equally to this work as co-senior authors.

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