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- RE: High-does Vitamin C
Vitamin C acts under physiological dosages as an antioxidant and works in the soluble, aqueous phase. Oxidized Vit C will get regenerated by the fat soluble Vit E which in turn is transformed from the oxidized stage into the reduced one by the Glutathione oxidase/reductase.
Thus, if one exceeds the regenerative capacity of the next compound (here Vit E) an overload of oxidized Vit C stays in action as a radical. Since tumours lack the antioxidative capacity needed to survive in a chronic low oxygen environment radiation and conventional chemotherapy work by inducing oxygen radicals.
This might also be the effect if Vit E administered in lung tumours shortens the life expectancy.Competing Interests: None declared.
