JAK inhibition increases bone mass in steady-state conditions and ameliorates pathological bone loss by stimulating osteoblast function

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  JAK inhibition increases bone mass in steady-state conditions and ameliorates pathological bone loss by stimulating osteoblast function

  By Susanne Adam, Nils Simon, Ulrike Steffen, Fabian T. Andes, Carina Scholtysek, Dorothea I. H. Müller, Daniela Weidner, Darja Andreev, Arnd Kleyer, Stephan Culemann, Madelaine Hahn, Georg Schett, Gerhard Krönke, Silke Frey, Axel J. Hueber

  Science Translational Medicine12 Feb 2020

  JAK inhibition enhances the function of bone-forming osteoblasts, increases bone mass, and induces repair of arthritic bone erosions.

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  JAK inhibition increases bone mass in steady-state conditions and ameliorates pathological bone loss by stimulating osteoblast function

  By Susanne Adam, Nils Simon, Ulrike Steffen, Fabian T. Andes, Carina Scholtysek, Dorothea I. H. Müller, Daniela Weidner, Darja Andreev, Arnd Kleyer, Stephan Culemann, Madelaine Hahn, Georg Schett, Gerhard Krönke, Silke Frey, Axel J. Hueber

  Science Translational Medicine12 Feb 2020

  JAK inhibition enhances the function of bone-forming osteoblasts, increases bone mass, and induces repair of arthritic bone erosions.

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